Players can buy the clothes - known as skins – to adorn in-game characters.
Tencent-owned developer TiMi Studios collaborated with the designer for its multiplayer online battle game Honor of Kings.
The new skins - which feature Burberry's signature trench coat and tartan - will be available in mainland China only.
“By allowing our Chinese customers to explore virtual products through the medium of online games, we can connect with our communities in a way that really resonates with them,” Josie Zhang, president of Burberry in China, said.