Video shot by an onlooker at the airport showed a fireball exploding out of the damaged aircraft and recorded the startled cries of people watching.
The pilot and copilot escaped harm using a rope ladder on the right side of the aircraft, according to Mike Jachles of Broward Sheriff Fire Rescue. No members of the ground crews were hurt, he added.
The fire occurred after the plane's landing gear collapsed as it touched ground, the FAA said. The Boeing MD-10 was operating as Flight 910 from Memphis, Tennessee, where FedEx is based.