Stormzy, Cat Burns, The 1975 and dance producer Fred Again are close behind with three apiece.
BBC reports Beyoncé and Taylor Swift will fight it out in the international categories, while Sam Ryder is in the running for best new artist.
He is the first Eurovision act ever to be recognised in the category.
"Well, I never knew that," Ryder told BBC News. "So the shock and awe on my stupid face is completely legitimate. That's amazing."
The star added that he had had a "funny relationship" with the Brits in his formative years as a musician.