Three of the accused are current employees of Prime Focus Technology, while one is a former employee.
Prime Focus, a Mumbai-based company that stores and processes the series for Indian streaming website Hotstar, had lodged a complaint with police.
The fantasy series is already the most pirated show in TV history.
Episode four of the seventh season was leaked on 4 August, days before it was due to air globally.
The show produced by HBO has seen several leaks over the years.
