The Ministry of Health said the symptoms are consistent with multiple illnesses including chickenpox and hand-foot-mouth-disease.
The ministry is investigating the cases saying they are contagious and spread quickly among children aged five years and under.
Chickenpox and Hand-Foot and Mouth disease are spread through person to person contact.
A local senior doctor, Esmay Judith Ah Leong also confirmed that a significant number of infants and children with chickenpox-like or varicella like lesions were admitted to her private clinic last week.
