The 25 year old has not put on the blue jersey due to injury since the Paris Sevens in June 2019, and he missed the Pacific Games and crucial Oceania Sevens Olympic qualifier.
Afamasaga also missed the opening two legs of the 2019/20 World Rugby Sevens Series, where Samoa slipped from a fourth-place finish in Dubai to 13th place in Cape Town.
But he is now fit and should be available for selection at the Hamilton Sevens on Saturday.
Also expected to make his return in the upcoming tournament is playmaker, Melani Matavao.
