Up until April 2015, Klitschko had only lost three of his 67 professional fights, but he was then beaten by two British fighters - Tyson Fury and Anthony Joshua.
His final defeat to Joshua at Wembley was considered by many as a classic heavyweight title fight, with both men sent to the canvas during the bout.
However, in the 11th round there was no way back for Klitschko as Joshua unleashed a barrage of punches that left the Ukrainian beaten.