In a bout that completely defied the pre-fight predictions of an easy Mayweather victory, the American showed his class as the rounds progressed to earn the bragging rights at the T-Mobile Arena.
Many had predicted that UFC star McGregor would be out of his depth against one of boxing's all-time pound-for-pound kings on his professional debut in the squared circle.
But the Irishman looked accustomed in the ring early in the contest and clearly had Mayweather confused with his unorthodox, wily style and there were signs that the mother of all upsets was on the cards.