The man was "an experienced bomb maker and operational facilitator", a coalition statement said.
Officials told US media that he was named Hani Ahmed al-Kurdi.
A monitoring group said troops were dropped by two helicopters in al-Humayra, close to the Turkish border in opposition-held Aleppo province.
There were seven minutes of armed clashes between the troops and people inside the village before the helicopters flew off, the UK-based Syrian Observatory for Human Rights reported.
